This book is specifically written for Toulouse by the group Americans in Toulouse. It seems very thorough about covering all sorts of things--how driving works, medical, real estate, etc, etc. I've just started reading it, getting ready for a possible move to Toulouse and I wanted to share it as a resource to all who are considering a move to France. I've lived near Paris for 4 years and also like 'At Home in Paris' by the Junior Service League of Paris as a reference but 'The Art of Living in Toulouse' is actually online so you can start your reading right away. You also can order the printed book from the AIT, info on the website.
http://www.geocities.com/aitonline/contents.html